GARP was shown to be involved in enhancing the suppressive phenotype of Tregs and in maintaining Treg-mediated peripheral tolerance
the IL-1beta/IL-1F2 present in the sample binds to the solid phase antibody and the detection antibody to form an immune complex
with N-terminal 8*His MHHHHHHHHMALSKVKLNDTLNKDQLLSSSKYTIQRSTGDNIDTPNYDVQKHLNKLCGMLLITEDANHKFTGLIGMLYAMSRLGREDTIKILKDAGYHVKANGVDITTYRQDINGKEMKFEVLTLSSLTSEIQVNIEIESRKSYKKLLKEMGEVAPEYRHDSPDCGMIILCIAALVITKLAAGDRSGLTAVIRRANNVLKNEIKRYKGLIPKDIANSFYEVFEKHPHLIDVFVHFGIAQSSTRGGSRVEGIFAGLFMNAYGSGQVMLRWGVLAKSVKNIMLGHASVQAEMEQVVEVYEYAQKLGGEAGFYHILNNPKASLLSLTQFPNFSSVVLGNAAGLGIMGEYRGTPRNQDLYDAAKAYAEQLKENGVINYSVLDLTAEELEAIKHQLNPKEDDVEL Expression System E
particularly haematological malignancies such as hairy cell leukaemia and chronic myelogenous leukaemia
E-cadherin exerts its tumour suppressing role mainly by sequestering β-catenin from its binding to LEF (Lymphoid enhancer factor)/TCF (T cell factor) which serves the function of transcribing genes of the proliferative Wnt signaling pathway
LCN2/NGAL His Tag Protein, Mouse Size:100μg GARP was shown to beProduct Specification Species Mouse Antigen LCN2 NGAL Synonyms NGAL, LCN2, Lipocalin 2, 24p3, MSFI Accession P11672 Amino Acid Sequence Gln21 Asn200, with C terminal 8*His QDSTQNLIPAPSLLTVPLQPDFRSDQFRGRWYVVGLAGNAVQKKTEGSFTMYSTIYELQENNSYNVTSILVRDQDQGCRYWIRTFVPSSRAGQFTLGNMHRYPQVQSYNVQVATTDYNQFAMVFFRKTSENKQYFKITLYGRTKELSPELKERFTRFAKSLGLKDDNIIFSVPTDQCIDNGGGSHHHHHHHH Expression System HEK293 Molecular Weight 25 28kDa Purity 95% by SDS PAGE Endotoxin <0.