When homeostasis is disrupted by infections or tissue injuries
and is associated with type 2 diabetes
The OPN-integrin binding can trigger downstream macrophage activities including TNF secretion
Reference 1、Brown E J
Studies of mouse and rat homologous protein implicated roles in morphogenesis of epithelium
Biotinylated CA125/MUC16 His&Avi Tag Protein, Human Interleukins When homeostasis is disrupted byProduct Specification Species Human Synonyms CA125, CA 125, MUC 16, FLJ14303, MUC16, mucin 16, mucin 16 Accession Q8WXI7 Amino Acid Sequence Pro13810 Pro14451, with C terminal His and Avitag Expression System HEK293 Molecular Weight 95 115kDa (Reducing) Purity 95% by SDS PAGE & >90% by SEC HPLC Endotoxin <0. 1EU g Tag Avi Tag, His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, 5% trehalose, PH7. 4 Reconstitution Reconstitute at 0. 1 1